Acute Complex Neuroplegia and Ophthalmoplegia Associated with Anti-GQ1b Antibodies
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Azeem S Sheikh 1 *
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1 Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, Essex, UK* Corresponding Author

Abstract

A 24-year-old gentleman presented with a history of severe throbbing headache preceded by sore throat. He was noted to have a nasal twang and dysphagia. He progressively developed weakness of all four limbs associated with ophthalmoplegia. He, subsequently, had to be intubated and ventilated in view of the involvement of the respiratory muscles. His anti-GQ1b antibodies were positive and the diagnosis of Bickerstaff brainstem encephalitis associated with Miller Fisher Syndrome overlapping with Guillain-Barre syndrome was confirmed. He was treated with intravenous Immunoglobulins 0.4 gm/kg/day for 5 days which resulted in a gradual recovery from his neurologic weakness.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

EUR J GEN MED, Volume 9, Issue 4, October 2012, 274-276

https://doi.org/10.29333/ejgm/82445

Publication date: 10 Oct 2012

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