ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES

Muaz Belviranlı; Hakkı Gökbel

doi:10.29333/ejgm/82392

Full Text (PDF)

Muaz Belviranlı ¹ ^* , Hakkı Gökbel ¹

More Detail

¹ Selcuk University, Meram Faculty of Medicine, Department of Physiology, Konya Turkey^* Corresponding Author

Abstract

Generation of reactive oxygen species (ROS) is a normal process. Under physiological conditions, these deleterious species are mostly removed by the cellular antioxidant systems, which include antioxidant vitamins, protein and non-protein thiols, and antioxidant enzymes. An acute bout of exercise at sufficient intensity has been shown to stimulate activities of antioxidant enzymes. This could be considered as a defensive mechanism of the cell under oxidative stress. However, we still have insufficient knowledge about the interaction between exercise and antioxidants, which are important in assessing the adequacy of protection against oxidative damage and about the necessity of dietary manipulation and/or supplementation. This review concerns effects of acute exercise on various oxidative stress parameters and antioxidant defense system.

Keywords

Acute exercise
Oxidative Stress
antioxidant status
lipid peroxidation
Antioxidant supplementation

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

EUR J GEN MED, Volume 3, Issue 3, July 2006, 126-131

https://doi.org/10.29333/ejgm/82392

Publication date: 15 Jul 2006

Article Views: 2715

Article Downloads: 2195

Open Access References How to cite this article

References

Urso ML, Clarkson PM. Oxidative stress, exercise, and antioxidant supplementation. Toxicology 2003;189(1- 2):41-54
Bloomer RJ, Goldfarb AH, Wideman L, McKenzie MJ, Consitt LA. Effects of acute aerobic and anaerobic exercise on blood markers of oxidative stress. J Strength Cond Res 2005;19(2):276-85
Alessio HM, Hagerman AE, Fulkerson BK, Ambrose J, Rice RE, Wiley RL. Generation of reactive oxygen species after exhaustive aerobic and isometric exercise. Med Sci Sports Exerc 2000;32(9):1576-81
Radak Z, Sasvari M, Nyakas C et al. Single bout of exercise eliminates the immobilization-induced oxidative stress in rat brain. Neurochem Int 2001;39(1): 33-8
Quindry JC, Stone WL, King J, Broeder CE. The effects of acute exercise on neutrophils and plasma oxidative stress. Med Sci Sports Exerc 2003;35(7):1139- 45
Deaton CM, Marlin DJ Exerciseassociated oxidative stress. Clin Tech Equine Prac 2003;2(3),278-91
Ilhan N, Kamanli A, Ozmerdivenli R, Ilhan N. Variable effects of exercise intensity on reduced glutathione, thiobarbituric acid reactive substance levels, and glucose concentration. Arch Med Res 2004;35(4):294-300
Mastaloudis A, Morrow JD, Hopkins DW, Devaraj S, Traber MG. Antioxidant supplementation prevents exerciseinduced lipid peroxidation, but not inflammation, in ultramarathon runners. Free Radic Biol Med 2004;36(10):1329- 41
Ashton T, Young IS, Peters JR et al. Electron spin resonance spectroscopy, exercise, and oxidative stress: an ascorbic acid intervention study. J Appl Physiol 1999;87(6):2032-6
Alessio HM, Goldfarb AH, Cultler RG. MDA content increases in fast- and slowtwitch skeletal muscle with intensity of exercise in a rat. Am J Physiol 1988;255(6 Pt 1):874-7
Ortenblad N, Madsen K, Djurhuus MS. Antioxidant status and lipid peroxidation after short-term maximal exercise in trained and untrained humans. Am J Physiol 1997;272(4 Pt 2):1258-63
Groussard C, Rannou-Bekono F, Machefer G et al. Changes in blood lipid peroxidation markers and antioxidants after a single sprint anaerobic exercise. Eur J Appl Physiol 2003;89(1):14-20
Radak Z, Nakamura A, Nakamoto H et al. A period of anaerobic exercise increases the accumulation of reactive carbonyl derivatives in the lungs of rats. Pflugers Arch 1998;435(3):439-41
Mastaloudis A, Leonard SW, Traber MG. Oxidative stress in athletes during extreme endurance exercise. Free Radic Biol Med 2001;31(7):911-22
Umegaki K, Daohua P, Sugisawa A, Kimura M, Higuchi M. Influence of one bout of vigorous exercise on ascorbic acid in plasma and oxidative damage to DNA in blood cells and muscle in untrained rats. J Nutr Biochem 2000;11(7-8):401-7
Oh-ishi S, Kizaki T, Ookawara T et al. Endurance training improves the resistance of rat diaphragm to exerciseinduced oxidative stress. Am J Respir Crit Care Med 1997;156(5):1579-85
Liu J, Yeo HC, Overvik-Douki E et al. Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants. J Appl Physiol 2000;89(1):21-8
McAnulty SR, McAnulty LS, Nieman DC, Morrow JD, Utter AC, Dumke CL. Effect of resistance exercise and carbohydrate ingestion on oxidative stress. Free Radic Res 2005;39(11):1219-24
Aguilo A, Tauler P, Fuentespina E, Tur JA, Cordova A, Pons A. Antioxidant response to oxidative stress induced by exhaustive exercise. Physiol Behav 2005;84(1):1-7
Alessio HM, Hagerman AE, Nagy S et al. Exercise improves biomarkers of health and stress in animals fed ad libitum. Physiol Behav 2005;84(1):65-72
Camus G, Felekidis A, Pincemail J et al. Blood levels of reduced/oxidized glutathione and plasma concentration of ascorbic acid during eccentric and concentric exercises of similar energy cost. Arch Int Physiol Biochim Biophys 1994;102(1):67-70
Somani SM, Frank S, Rybak LP. Responses of antioxidant system to acute and trained exercise in rat heart subcellular fractions. Pharmacol Biochem Behav 1995;51(4): 627-34
Tauler P, Aguilo A, Gimeno I, Guix P, Tur JA, Pons A. Different effects of exercise tests on the antioxidant enzyme activities in lymphocytes and neutrophils. J Nutr Biochem 2004;15(8):479-84
Sureda A, Tauler P, Aguilo A et al. Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise. Free Radic Res 2005;39(12):1317-24
Terblanche SE. The effects of exhaustive exercise on the activity levels of catalase in various tissues of male and female rats. Cell Biol Int 2000;23(11):749-53
Sureda A, Tauler P, Aguilo A et al. Blood cell NO synthesis in response to exercise. Nitric Oxide 2005; Epub ahead of print
Ramel A, Wagner KH, Elmadfa I. Plasma antioxidants and lipid oxidation after submaximal resistance exercise in men. Eur J Nutr 2004;43(1):2-6
Watson TA, Callister R, Taylor RD, Sibbritt DW, MacDonald-Wicks LK, Garg ML. Antioxidant restriction and oxidative stress in short-duration exhaustive exercise. Med Sci Sports Exerc 2005;37(1):63-71
Davies KJ, Quintanilha AT, Brooks GA, Packer L. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 1982;107(4):1198-205
Tiidus PM, Houston ME. Vitamin E status does not affect the responses to exercise training and acute exercise in female rats. J Nutr 1993;123(5):834-40
McBride JM, Kraemer WJ, TriplettMcBride T, Sebastianelli W. Effect of resistance exercise on free radical production. Med Sci Sports Exerc 1998;30(1):67-72
McAnulty SR, McAnulty LS, Nieman DC et al. Effect of alpha-tocopherol supplementation on plasma homocysteine and oxidative stress in highly trained athletes before and after exhaustive exercise. J Nutr Biochem 2005;16(9): 530-7
Greathouse KL, Samuels M, Dimarco NM, Criswell DS. Effects of increased dietary fat and exercise on skeletal muscle lipid peroxidation and antioxidant capacity in male rats. Eur J Nutr 2005;44(7):429- 435
Vollaard NB, Shearman JP, Cooper CE Exercise-induced oxidative stress: myths, realities and physiological relevance. Sports Med 2005;35(12):1045-62
Leeuwenburgh C, Heinecke JW. Oxidative stress and antioxidants in exercise. Curr Med Chem 2001;8(7):829-38

How to cite this article

Vancouver

Belviranlı M, Gökbel H. ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES. EUR J GEN MED. 2006;3(3):126-31. https://doi.org/10.29333/ejgm/82392

APA

Belviranlı, M., & Gökbel, H. (2006). ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES. European Journal of General Medicine, 3(3), 126-131. https://doi.org/10.29333/ejgm/82392

AMA

Belviranlı M, Gökbel H. ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES. EUR J GEN MED. 2006;3(3), 126-131. https://doi.org/10.29333/ejgm/82392

Chicago

Belviranlı, Muaz, and Hakkı Gökbel. "ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES". European Journal of General Medicine 2006 3 no. 3 (2006): 126-131. https://doi.org/10.29333/ejgm/82392

Harvard

Belviranlı, M., and Gökbel, H. (2006). ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES. European Journal of General Medicine, 3(3), pp. 126-131. https://doi.org/10.29333/ejgm/82392

MLA

Belviranlı, Muaz et al. "ACUTE EXERCISE INDUCED OXIDATIVE STRESS AND ANTIOXIDANT CHANGES". European Journal of General Medicine, vol. 3, no. 3, 2006, pp. 126-131. https://doi.org/10.29333/ejgm/82392

Electronic Journal of General Medicine

Abstract

Keywords

License