Biomarkers and clinical features associated with pressure injury among geriatric patients
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Khalid Elsayed Elsorady 1 2 * , Ahmed Hassan Nouh 3
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1 Department of Geriatrics and Gerontology, Faculty of Medicine, Ain Shams University, Cairo, EGYPT2 Geriatrics Hospital, Ain Shams University Hospitals, Abbasia, Cairo, EGYPT3 Department of Dermatology and Venereology, Al Azhar University, Cairo, EGYPT* Corresponding Author

Abstract

Purpose: The study aims to identify biomarkers and clinical features associated with pressure injury (PI) among geriatric patients.
Methods: A cross-sectional study including 191 patients aged ≥60 years. Patients were classified into those with and without PI. Assessing the risk of PI was performed on admission by applying the Braden scale (BS) for predicting pressure sore risk. Clinical history, baseline hematology, and biochemistry results were obtained. C-reactive protein to albumin ratio (CAR) and Charlson comorbidity index (CCI) were calculated. Statistical analyses were performed.
Results: 43 (22.5%) patients had PI. PI was significantly associated with higher CCI, total leukocyte count, and CAR, besides lower BS scores, serum albumin, and total proteins. Significant comorbidities were diabetes mellitus, stroke/transient ischemic attack, dementia, incontinence, and chronic kidney disease. The optimal cut-offs for PI occurrence were ≤14, ≤3.1 g/dl and >1.27 for BS, albumin, and CAR, respectively.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 20, Issue 1, February 2023, Article No: em431

https://doi.org/10.29333/ejgm/12636

Publication date: 01 Jan 2023

Online publication date: 13 Nov 2022

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Article Downloads: 1181

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