BUPROPION HYDROCHLORIDE INDUCED SERUM SICKNESS-LIKE REACTION
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Ayşe Cefle 1 * , Ayten Yazıcı 1
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1 Kocaeli University School of Medicine, Department of Internal Medicine, Division of Rheumatology, Kocaeli, Turkey* Corresponding Author

Abstract

Sustained-release bupropion is commonly used for the symptomatic relief of depressive disorders and as an adjuvant in smoking cessation therapy. The frequency of adverse reactions with bupropion has been estimated to be more than 1%. Hypersensitivity reactions to bupropion are fairly common and include rare cases of serum sickness-like reaction. Here we report a case of bupropion hydrochloride induced serum sickness-like reaction. Complete resolution of symptoms was achieved on discontinuing bupropion and instituting therapy with glucocorticoid and a non-steroidal antiinflammatory drug.We report this case to notify clinicians of potential serious multisystem complications that can occur with sustained-release bupropion therapy.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, Volume 3, Issue 4, October 2006, 184-185

https://doi.org/10.29333/ejgm/82406

Publication date: 15 Oct 2006

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Article Downloads: 1046

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