Cerebral venous thrombosis in Behçet’s disease: A study of 17 cases
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Mouna Snoussi 1 * , Abir Chatti 1 , Mayeda Ben Hmad 1 , Wiem Feki 2 , Zeineb Mnif 2 , Faten Frikha 1 , Sameh Marzouk 1 , Zouhir Bahloul 1
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1 Department of Internal Medicine, Medical School of Sfax, Sfax, TUNISIA2 Department of Radiology, Medical School of Sfax, Sfax, TUNISIA* Corresponding Author

Abstract

Introduction: Cerebral sinus thrombosis is an uncommon neurologic condition caused by many etiologies. Behçet’s disease (BD) is one of the leading causes in Mediterraneen and Middle Eastern countries. The aim of our study was to summarize the clinical manifestation, the therapeutic strategies and the prognosis of cerebral sinus thrombosis of BD in southern Tunisia.
Patients and methods: This is a descriptive study of patients followed for BD complicated with cerebral sinus thrombosis in the department of internal medicine of Hedi Chaker Hospital in Tunisia. The study was conducted during a period of 24 years (January 1996 to December 2021). Statistical study was performed with SPSS 2022.
Results: 17 patients were enrolled with a mean age of 28 years and male predominance noted in 88% of cases. The most common mode of onset was subcute in 41% of cases. 53% of patients had intracranial hypertension. Transverse sinus and longitudinal sinus were the most affected in 59% and 47% of cases. Anticoagulation was the basis of the treatment in all patients. The specific treatment was based on colchicine in all patients, corticotherapy in 14 patients and cyclophosphamide was administered in four patients with ocular manifestation. Outcome was good in all patients with no relapses or death.
Conclusion: In southern Tunisia cerebral sinus thrombosis in BD is predominant in male young patients. It has a subacute presentation dominated by intracranial hypertension and the prognosis is good under anticoagulation and etiological treatment.

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Article Type: Original Article

ELECTRON J GEN MED, Volume 22, Issue 2, April 2025, Article No: em639

https://doi.org/10.29333/ejgm/16061

Publication date: 01 Mar 2025

Online publication date: 26 Feb 2025

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