Evaluation of the Effects of Magnesium Sulfate on Prevention of Post-dural-Puncture Headache in Elective Cesarean in Kamali Hospital
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Banafsheh Mashak 1, Seyyed Mohsen Pouryaghobi 1, Mehdi Rezaee 2, Samira Saee Rad 3, Mina Ataei 4 * , Aida Borzabadi 5
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1 Assistant Professor of Anesthesioligy, Alborz University of Medical Sciences, Karaj, IRAN2 Department of Anesthesioligy, Alborz University of Medical Sciences, Karaj, IRAN3 Medical Geneticist, Saee rad genetic laboratory, Karaj, Alborz, IRAN4 Assistant Professor, Infertility Fellowship, Obstetrics and Gynecology, Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, IRAN5 Student Research Committee, Alborz University of Medical Science, Karaj, IRAN* Corresponding Author

Abstract

Introduction: One of the most common complications of spinal anesthesia in elective cesarean is a headache, known commonly as post-dural-puncture headache (PDPH). Various methods are mainly recommended such as resting and the use of non-opioid analgesics, caffeine, and codeine, but none of them has been fully effective in its treatment. Hence, this study was conducted to evaluate the effect of magnesium sulfate on the prevention of post-dural-puncture headache in the elective cesarean.
Method: a total of 68 patients candidate for elective cesarean and admitted to Kamali Hospital were selected using convenient sampling and they were randomly divided into two groups. One group received magnesium and other group received saline. Subjects of case group received magnesium at the dose of 50 mg / kg as bolus and the subjects of control group received normal saline at the same dose as bolus. The incidence of headache and its severity 12, 24, 36, 48 ​​, 60 and 72 hours after surgery were measured in both case and control groups.
Results: The mean age of patients in the magnesium sulfate group was 27.94 years with a standard deviation of 5.18 and the mean age of patients in the normal saline group was 29.35 years with a standard deviation of 5.97. The mean body mass index (BMI) in the magnesium sulfate group was 26.34 with a standard deviation of 4.03 and the mean body mass index (BMI) in the normal saline group was 27.15 with a standard deviation of 2.47. Post-dural-puncture headache severity was lower in the case group than that in the control group at all times (P <0.05).
Conclusion: The results of this study revealed that intravenous administration of magnesium sulfate before elective cesarean in patients undergoing spinal anesthesia significantly decreases the severity of post-dural-puncture headache (PDPH).

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 17, Issue 3, June 2020, Article No: em199

https://doi.org/10.29333/ejgm/7847

Publication date: 21 Mar 2020

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