Factors Associated with Early-onset Neonatal Sepsis in Children of Peruvian Military Personnel
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César A. Mogollón 1, Evelyn E. Bautista 2, Gustavo Hernández-Arriaga 3, Lotty Bueso-Pineda 4, Marcos Roberto Tovani-Palone 5, Christian R. Mejia 6 *
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1 Universidad Nacional de Cajamarca, Cajamarca, Peru2 Sociedad Científica de Estudiantes de Medicina de Cajamarca, Universidad Nacional de Cajamarca, Cajamarca, Peru3 Facultad de Medicina y Cirugía, Universidad Católica de Honduras, San Pedro Sula, Honduras4 School of Nursing, Trinity Western University, Langley, BC, Canada5 Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil6 Universidad Continental, Lima, Peru* Corresponding Author

Abstract

Introduction:
The risk factors for early-onset neonatal sepsis (EOS) are well known. However, they have still not been evaluated in children of military personnel, which are a special population.

Objective:
To determine factors associated with EOS in children of Peruvian military personnel in a hospital.

Materials and Methods:
This is an observational, analytical, and retrospective study that included neonates hospitalized in the Neonatal Unit of the Hospital Militar Central, Peru between 2009 and 2017. Data were compiled from clinical history and hospital stay records. Sepsis cases were cross-checked against other variables of interest via generalized linear models.

Results:
Out of a total of 2,371 included neonates, 114 neonates were diagnosed with EOS. There was an increased frequency of neonatal sepsis with longer neonatal hospital stay (adjusted prevalence ratio (aPR): 1.21; 95% confidence interval (CI): 1.15–1.28; p<0.001), greater gestational age (aPR: 1.03; 95% CI: 1.01–1.05; p =0.003), and development of urinary tract infection in pregnant women in the third trimester of pregnancy (aPR: 2.27; 95% CI: 1.39–3.73; p=0.003). In contrast, there was a lower incidence of neonatal sepsis in female neonates (aPR: 0.64; 95% CI: 0.42–0.99; p=0.044).

Conclusions:
The associated factors with EOS in children of Peruvian military personnel were sex, longer neonatal hospital stay, gestational age and development of urinary tract infection in pregnant women during the third trimester of pregnancy. The aforementioned information is significant in describing this neonate population.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 16, Issue 5, October 2019, Article No: em156

https://doi.org/10.29333/ejgm/114059

Publication date: 06 Nov 2019

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Article Downloads: 3138

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