Mean Platelet Volume Level in Patients with Ankylosing Spondylitis and its Relationship with Disease Activity and Presence of Cardiovascular Risk Factors
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Nilgun Ustun 1 * , Alper Murat Ulasli 2, Ihsan Ustun 3, Erkan Yula 4, Abdullah Erman Yagiz 1, Hayal Guler 1
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1 Department of General Surgery, Kecioren Training and Research Hospital Ankara, Turkey2 Department of Gastroenterology, Çanakkale Public Hospital, Ankara, Turkey3 Department of Surgery, Yıldırım Beyazıt University, Faculty of Medicine, Ankara, Turkey4 Department of Gastroenterology, Hacettepe University, Faculty of Medicine, Ankara, Turkey* Corresponding Author

Abstract

This study was conducted to compare mean platelet volume (MPV) in ankylosing spondylitis (AS) patients with that of healty controls, analyze the effect of disease status and presence of traditional cardiovascular risk factors (CRF) such as smoking, hypertension, hyperlipidemia, diabetes and obesity. Retrospectively, 152 patients with AS were included. The control group included 55 sex-and age-matched healty subjects without any risk factors and concomitant diseases. MPV level in AS patients was higher than healthy controls, MPV and PLT levels in AS patients with at least on one traditional CRF were not significantly different compared to patients without any risk factor. MPV showed no significant association with any disease activity. There was no significant difference between active and inactive state in AS patients according to MPV. Patients have higher MPV than healthy controls indicating higher risk of cardiovascular involvement and atherosclerosis. AS alone may be responsible of this increment instead of traditional CRF’s.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, Volume 11, Issue 4, October 2014, 239-243

https://doi.org/10.15197/sabad.1.11.79

Publication date: 15 Oct 2014

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