Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis

Joan A Loayza-Castro; Luisa Erika Milagros Vásquez-Romero; Gianella Zulema Zeñas-Trujillo; Victor Juan Vera-Ponce; Jenny Raquel Torres-Malca; Norka Rocío Guillén-Ponce; Jamee Guerra Valencia; Willy Ramos; Jhony A De La Cruz-Vargas

doi:10.29333/ejgm/13815

Joan A Loayza-Castro ¹ , Luisa Erika Milagros Vásquez-Romero ¹ , Gianella Zulema Zeñas-Trujillo ¹ , Victor Juan Vera-Ponce ¹ ^* , Jenny Raquel Torres-Malca ¹ , Norka Rocío Guillén-Ponce ¹ , Jamee Guerra Valencia ¹ , Willy Ramos ¹ , Jhony A De La Cruz-Vargas ¹

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¹ Instituto de Investigaciones en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, PERU^* Corresponding Author

Abstract

Introduction: Obstructive sleep apnea (OSA) is related to chronic kidney disease (CKD), but its association is not fully understood.
Objective: To realize a systematic review with meta-analysis to determine the association between OSA and CKD.
Methods: Systematic review with meta-analysis of observational studies. The search was carried out in Embase, PubMed/Medline, Scopus, and Web of Science. The data were calculated by the hazard ratio (HR). The heterogeneity was identified by I squared.
Results: Five studies were included (n=6,710). The meta-analysis found an association between OSA and CKD (HR=2.00; confidence interval 95%=1.68-2.38).
Conclusions: We found an association between OSA and CKD.

Keywords

obstructive sleep apnea
chronic kidney disease
systematic review

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

ELECTRON J GEN MED, Volume 20, Issue 6, December 2023, Article No: em550

https://doi.org/10.29333/ejgm/13815

Publication date: 01 Nov 2023

Online publication date: 19 Oct 2023

Article Views: 1522

Article Downloads: 703

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References

Hui L, Benca R. The bidirectional relationship between obstructive sleep apnea and chronic kidney disease. J Stroke Cerebrovasc Dis. 2021;30(9):105652. https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105652 PMid:33608118
Setareh J, Mehrnia M, Mirabi A. The risk of obstructive sleep apnea and daytime sleepiness in patients with cardiovascular disease. J Mazandaran Univ Med Sci. 2018; 28(167):29-41. (Available at: http://jmums.mazums.ac.ir/article-1-11632-en.pdf )
Huang H-C, Walters G, Talaulikar G, et al. Sleep apnea prevalence in chronic kidney disease-association with total body water and symptoms. BMC Nephrol. 2017;18:125. https://doi.org/10.1186/s12882-017-0544-3 PMid:28376734 PMCid:PMC5381077
Xie Y, Bowe B, Mokdad AH, et al. Analysis of the global burden of disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016. Kidney Int. 2018;94(3):567-81. https://doi.org/10.1016/j.kint.2018.04.011 PMid:30078514
Coresh J. Update on the burden of CKD. J Am Soc Nephrol. 2017;28(4):1020-2. https://doi.org/10.1681/ASN.2016121374 PMid:28302756 PMCid:PMC5373470
Agudelo-Botero M, Valdez-Ortiz R, Giraldo-Rodríguez L, et al. Overview of the burden of chronic kidney disease in Mexico: Secondary data analysis based on the global burden of disease study 2017. BMJ Open. 2020;10(3): e035285. https://doi.org/10.1136/bmjopen-2019-035285 PMid:32213523 PMCid:PMC7170614
Atamari-Anahui N, Ccorahua-Rios MS, Condori-Huaraka M, Huamanvilca-Yepez Y, Amaya E, Herrera-Añazco P. Epidemiology of chronic kidney disease in Peru and its relation to social determinants of health. Int Health. 2019; 12(4):264-71. https://doi.org/10.1093/inthealth/ihz071 PMid:31670810 PMCid:PMC7322196
Moradzadeh M, Mirmohammadkhani M, Tamadon MR, Mansori K, Malek F. Prevalence of sleep apnea and its associated factors in chronic kidney disease patients. Tanaffos. 2021;20(2):116-25. PMid: 34976082; PMCid: PMC8710220
Molnar MZ, Mucsi I, Novak M, Szabo Z, Freire AX, Huch KM, et al. Association of incident obstructive sleep apnoea with outcomes in a large cohort of US veterans. Thorax. septiembre de 2015;70(9):888-95. https://doi.org/10.1136/thoraxjnl-2015-206970 PMid:26038534 PMCid:PMC4575815
Lee YC, Hung SY, Wang HK, Lin CW, Wang HH, Chen SW, et al. Sleep Apnea and the Risk of Chronic Kidney Disease: A Nationwide Population-Based Cohort Study. Sleep. 1 de febrero de 2015;38(2):213-21. https://doi.org/10.5665/sleep.4400 PMid:25409108 PMCid:PMC4288602
Lee Y-J, Jang HR, Huh W, et al. Independent contributions of obstructive sleep apnea and the metabolic syndrome to the risk of chronic kidney disease. J Clin Sleep Med. 2017;13(10):1145-52. https://doi.org/10.5664/jcsm.6758 PMid:28760190 PMCid:PMC5612629
Chu H, Shih C-J, Ou S-M, Chou K-T, Lo Y-H, Chen Y-T. Association of sleep apnoea with chronic kidney disease in a large cohort from Taiwan. Respirology. 2016;21(4):754-60. https://doi.org/10.1111/resp.12739 PMid:26799629
Adams RJ, Appleton SL, Vakulin A, et al. Chronic kidney disease and sleep apnea association of kidney disease with obstructive sleep apnea in a population study of men. Sleep. 2017;40(1). https://doi.org/10.1093/sleep/zsw015
Nigam G, Pathak C, Riaz M. A systematic review of central sleep apnea in adult patients with chronic kidney disease. Sleep Breath. 2016;20:957-64. https://doi.org/10.1007/s11325-016-1317-0 PMid:26815045
Umbro I, Fabiani V, Fabiani M, Angelico F, Del Ben M. A systematic review on the association between obstructive sleep apnea and chronic kidney disease. Sleep Med Rev. 2020;53:101337. https://doi.org/10.1016/j.smrv.2020.101337 PMid:32629235
da Silva Cremasco G, Baptista MN. Depresión y enfermedad renal crónica: Revisión integrativa de la literature [Depression and chronic kidney disease: Integrative literature review]. Psicol Teor E Prática. 2018;20(3):360-76. https://doi.org/10.5935/1980-6906/psicologia.v20n3p360-376
de Araújo IM, da Silva EL, Magalhães ALP, DEça Júnior A, de Farias Nunes FBB, dos Santos EM. Deficiência de vitamina d e mortalidade cardiovascular na doença renal crônica: Revisão integrativa [Vitamin D deficiency and cardiovascular mortality in chronic kidney disease: Integrative review]. Ciênc Cuid Saúde. 2021:e50127. https://doi.org/10.4025/cienccuidsaude.v20i0.50127
Cueto-Manzano AM. La Sociedad Latinoamericana de Nefrología e Hipertensión y los retos de la enfermedad renal crónica en nuestra region [The Latin American Society of Nephrology and Hypertension and the challenges of chronic kidney disease in our region]. Nefrol Latinoam. 2019;16:13-9. https://doi.org/10.24875/NEFRO.18000053
Canales MT, Bozorgmehri S, Ishani A, Weiner ID, Berry R, Beyth R. Prevalence and correlates of sleep apnea among US Veterans with chronic kidney disease. J Sleep Res. 2020;29(4):e12981. https://doi.org/10.1111/jsr.12981 PMid:31912641
Raman M, Middleton RJ, Kalra PA, Green D. Estimating renal function in old people: An in-depth review. Int Urol Nephrol. 2017;49(11):1979-88. https://doi.org/10.1007/s11255-017-1682-z PMid:28913589 PMCid:PMC5643354
Ingram DG, Singh AV, Ehsan Z, Birnbaum BF. Obstructive sleep apnea and pulmonary hypertension in children. Paediatr Respir Rev. 2017;23:33-9. https://doi.org/10.1016/j.prrv.2017.01.001 PMid:28185814
Bitners AC, Arens R. Evaluation and management of children with obstructive sleep apnea syndrome. Lung. 2020;198(2):257-70. https://doi.org/10.1007/s00408-020-00342-5 PMid:32166426 PMCid:PMC7171982
Hunter SJ, Gozal D, Smith DL, Philby MF, Kaylegian J, Kheirandish-Gozal L. Effect of sleep-disordered breathing severity on cognitive performance measures in a large community cohort of young school-aged children. Am J Respir Crit Care Med. 2016;194(6):739-47. https://doi.org/10.1164/rccm.201510-2099OC PMid:26930303 PMCid:PMC5027230
Jamwal J, Qadri SM, Siraj F, Shah S. Prevalence of obstructive sleep apnea in patients with chronic kidney disease: A hospital-based study. Sleep Breath. 2023; 27(5):1703-8. https://doi.org/10.1007/s11325-022-02764-2 PMid:36576598
Voulgaris A, Marrone O, Bonsignore MR, Steiropoulos P. Chronic kidney disease in patients with obstructive sleep apnea. A narrative review. Sleep Med Rev. 2019;47:74-89. https://doi.org/10.1016/j.smrv.2019.07.001 PMid:31376590
Huang Z, Tang X, Zhang T, Qiu S, Xia Z, Fu P. Prevalence of sleep apnoea in non-dialysis chronic kidney disease patients: A systematic review and meta-analysis. Nephrology (Carlton). 2019;24(10):1041-9. https://doi.org/10.1111/nep.13546 PMid:30525256
Yayan J, Rasche K, Vlachou A. Obstructive sleep apnea and chronic kidney disease. In: Pokorski M, editor. Clinical management of pulmonary disorders and diseases. Advances in experimental medicine and biology. New York (NY): Springer; 2017. p. 11-8. https://doi.org/10.1007/5584_2017_35 PMid:28567615
Beaudin AE, Raneri JK, Ahmed S, et al. Association of insomnia and short sleep duration, alone or with comorbid obstructive sleep apnea, and the risk of chronic kidney disease. Sleep. 2022;45(7):zsac088. https://doi.org/10.1093/sleep/zsac088 PMid:35445715 PMCid:PMC9272259
Adeseun GA, Rosas SE. The impact of obstructive sleep apnea on chronic kidney disease. Curr Hypertens Rep. 2010;12:378-83. https://doi.org/10.1007/s11906-010-0135-1 PMid:20676805 PMCid:PMC2975904
Lin C-H, Perger E, Lyons OD. Obstructive sleep apnea and chronic kidney disease. Curr Opin Pulm Med. 2018;24(6): 549-54. https://doi.org/10.1097/MCP.0000000000000525 PMid:30239379
Somkearti P, Chattakul P, Khamsai S, et al. Predictors of chronic kidney disease in obstructive sleep apnea patients. Multidiscip Respir Med. 2020;15:470. https://doi.org/10.4081/mrm.2020.470 PMid:32153778 PMCid:PMC7037503
Seliger SL, Salimi S, Pierre V, Giffuni J, Katzel L, Parsa A. Microvascular endothelial dysfunction is associated with albuminuria and CKD in older adults. BMC Nephrol. 2016;17:82. https://doi.org/10.1186/s12882-016-0303-x PMid:27412615 PMCid:PMC4944235
Bouloukaki I, Mermigkis C, Tzanakis N, et al. Evaluation of inflammatory markers in a large sample of obstructive sleep apnea patients without comorbidities. Mediators Inflamm. 2017;2017:4573756. https://doi.org/10.1155/2017/4573756 PMid:28831208 PMCid:PMC5555019
Basoglu OK, Tasbakan MS. Gender differences in clinical and polysomnographic features of obstructive sleep apnea: A clinical study of 2827 patients. Sleep Breath. 2018;22:241-9. https://doi.org/10.1007/s11325-017-1482-9 PMid:28197893
Mehra S, Ghimire RH, Mingi JJ, et al. Gender differences in the clinical and polysomnographic characteristics among Australian aboriginal patients with obstructive sleep apnea. Nat Sci Sleep. 2020;12:593-602. https://doi.org/10.2147/NSS.S258330 PMid:32922104 PMCid:PMC7455593
Lin Y-S, Liu P-H, Lin S-W, et al. Simple obstructive sleep apnea patients without hypertension or diabetes accelerate kidney dysfunction: A population follow-up cohort study from Taiwan. Sleep Breath. 2017;21:85-91. https://doi.org/10.1007/s11325-016-1376-2 PMid:27380033 PMCid:PMC5343077
Drager LF, Santos RB, Silva WA, et al. OSA, short sleep duration, and their interactions with sleepiness and cardiometabolic risk factors in adults: The ELSA-Brasil study. Chest. 2019;155(6):1190-8. https://doi.org/10.1016/j.chest.2018.12.003 PMid:30948225
Lee C-H, Sethi R, Li R, et al. Obstructive sleep apnea and cardiovascular events after percutaneous coronary intervention. Circulation. 2016;133(21):2008-17. https://doi.org/10.1161/CIRCULATIONAHA.115.019392 PMid:27178625
Furlan SF, Sinkunas V, Damiani LP, et al. Obstructive sleep apnea, sleep duration and chronic kidney disease in patients with coronary artery disease. Sleep Med. 2021; 84:268-74. https://doi.org/10.1016/j.sleep.2021.05.025 PMid:34186452
Hansrivijit P, Puthenpura MM, Ghahramani N, Thongprayoon C, Cheungpasitporn W. Bidirectional association between chronic kidney disease and sleep apnea: A systematic review and meta-analysis. Int Urol Nephrol. 2021;53:1209-22. https://doi.org/10.1007/s11255-020-02699-1 PMid:33155087

How to cite this article

Vancouver

Loayza-Castro JA, Vásquez-Romero LEM, Zeñas-Trujillo GZ, Vera-Ponce VJ, Torres-Malca JR, Guillén-Ponce NR, et al. Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis. ELECTRON J GEN MED. 2023;20(6):em550. https://doi.org/10.29333/ejgm/13815

APA

Loayza-Castro, J. A., Vásquez-Romero, L. E. M., Zeñas-Trujillo, G. Z., Vera-Ponce, V. J., Torres-Malca, J. R., Guillén-Ponce, N. R., Guerra Valencia, J., Ramos, W., & De La Cruz-Vargas, J. A. (2023). Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis. Electronic Journal of General Medicine, 20(6), em550. https://doi.org/10.29333/ejgm/13815

AMA

Loayza-Castro JA, Vásquez-Romero LEM, Zeñas-Trujillo GZ, et al. Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis. ELECTRON J GEN MED. 2023;20(6), em550. https://doi.org/10.29333/ejgm/13815

Chicago

Loayza-Castro, Joan A, Luisa Erika Milagros Vásquez-Romero, Gianella Zulema Zeñas-Trujillo, Victor Juan Vera-Ponce, Jenny Raquel Torres-Malca, Norka Rocío Guillén-Ponce, Jamee Guerra Valencia, Willy Ramos, and Jhony A De La Cruz-Vargas. "Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis". Electronic Journal of General Medicine 2023 20 no. 6 (2023): em550. https://doi.org/10.29333/ejgm/13815

Harvard

Loayza-Castro, J. A., Vásquez-Romero, L. E. M., Zeñas-Trujillo, G. Z., Vera-Ponce, V. J., Torres-Malca, J. R., Guillén-Ponce, N. R., . . . De La Cruz-Vargas, J. A. (2023). Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis. Electronic Journal of General Medicine, 20(6), em550. https://doi.org/10.29333/ejgm/13815

MLA

Loayza-Castro, Joan A et al. "Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis". Electronic Journal of General Medicine, vol. 20, no. 6, 2023, em550. https://doi.org/10.29333/ejgm/13815