Partial Merosin Deficiency and Precocious Puberty
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Beray Selver Eklioglu 1 * , Nesibe Akyurek 2, Sevil Ari Yuca 3, Mehmet Emre Atabek 1
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1 Department of Pediatric Endocrinology and Diabetes, School of Medicine, Necmettin Erbakan University, Konya, Turkey2 Konya Education and Research Hospital, Konya, Turkey3 Department of Pediatric Endocrinology and Diabetes, School of Medicine, Selcuk University, Konya, Turkey* Corresponding Author

Abstract

The congenital muscular dystrophies (CMD) are autosomal-recessive disorders. Classical congenital muscular dystrophy is grouped as merosin-positive and merosin-negative (MN-CMD). Precocious puberty in girls has been defined by Marshal and Tanner in 1969. In most of the cases, precocious puberty is idiopathic and is related to premature release of gonadotrophins. So far, the association between merosin deficiency and precocious puberty has not been identified. We report a case of a child with precocious puberty who was diagnosed with merosin deficiency in infancy.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

EUR J GEN MED, Volume 12, Issue 1, January 2015, 90-92

https://doi.org/10.15197/sabad.1.12.18

Publication date: 07 Jan 2015

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