Prevalence of multidrug resistance pathogens in dermatology: A retrospective study in Romania, 2018-2022
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Alina-Viorica Iancu 1 2 3 , Nicoleta-Maricica Maftei 1 4 5 * , Caterina Dumitru 1 2 5 * , Liliana Baroiu 1 2 , Gabriela Gurau 1 3 4 , Alina Mihaela Elisei 1 5 , Claudia Simona Stefan 1 5 , Alin Laurentiu Tatu 1 2 6 , Alexandru-Florin Iancu 1 , Manuela Arbune 1 3
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1 Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, ROMANIA2 Clinical Hospital of Infectious Diseases “Sf. Cuvioasa Parascheva”, Galați, ROMANIA3 Research Laboratory of Microbiology, Imunology and Clinical Application of Infections Diseases, “Dunărea de Jos” University, Galați, ROMANIA4 Clinical Hospital of Children Hospital “Sf. Ioan”, Galați, ROMANIA5 Research Center in Medical-Pharmaceutical Field, “Dunărea de Jos” University, Galați, ROMANIA6 Multidisciplinary Integrated Center of Dermatological Interface Research Center, “Dunărea de Jos” University, Galați, ROMANIA* Corresponding Author

Abstract

Antimicrobial resistance (AMR) is now a major challenge to clinicians in treating patients. The purpose of our study was to determine the incidence of multidrug resistant (MDR) strains and antibiotic resistance profile in department of dermatology-venereology from a Romanian infectious disease’s hospital. We analyzed 1,152 bacterial strains, we obtained 34.5% MDR strains, identifying the following species: staphylococcus aureus 43.6%, enterococcus spp 16.7%, escherichia coli 31.0%, proteus spp 27.1%, klebsiella spp. 22.4%, pseudomonas spp. 34.8%. Overall, the rate of methicillin-resistant staphylococcus aureus was 76.1%; extended spectrum beta-lactamase production was 46.1% for escherichia coli and 66.0% for klebsiella pneumoniae; carbapenems-resistance was 51.0% for pseudomonas aeruginosa. All strains of E. coli and klebsiella were sensitive to meropenem. Our results confirm the high level of AMR, and continuous monitoring is essential for updating the local diagnostic and treatment protocols for dermatological infections.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 21, Issue 3, June 2024, Article No: em582

https://doi.org/10.29333/ejgm/14572

Publication date: 06 May 2024

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