Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome and Malignancy
Full Text (PDF)
Mehmet Sayarlıoğlu 1 *
More Detail
1 Yüzüncü Yıl University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Van, Turkey* Corresponding Author

Abstract

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a definite subset of the seronegative symmetrical polyarthritis of the aged, characterized by dramatic pitting edema of the hands, male predominance, old age and exquisite response to corticosteroids. RS3PE syndrome is a rare but well-defined syndrome known to be associated with solid tumors and haematologic malignancies. Recent research has shown that it is not a specific entity but rather a syndrome that can represent the inaugural form of various types of rheumatic disease and neoplastic conditions of the elderly. A thorough examination in elderly patients with RS3PE syndrome, and heightened suspicion of potential underlying malignant disease is necessary.

Keywords

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

EUR J GEN MED, Volume 1, Issue 2, April 2004, 3-5

https://doi.org/10.29333/ejgm/82184

Publication date: 15 Apr 2004

Article Views: 1616

Article Downloads: 1250

Open Access References How to cite this article