Abstract
Aim: Multiple sclerosis (MS) is an inflammatory demyelinating disease with unknown origin. Several studies suggest lower levels of serum uric acid (UA), an endogenous antioxidant, in MS patients. Methods: In this study, we aimed to investigate serum UA levels in relapsing-remitting (RR) MS. In addition we compared serum UA levels by means of clinical activity, expanded disability status scale (EDSS) and disease duration. Results: In the present study, mean serum UA levels were lower in RRMS and relapse patients with MS than in the other neurological diseases (OND) group, but the difference did not reach significance level. UA levels did not correlate with clinical activity, EDSS score and disease duration either in relapse or remitting or both of them. Conclusion: In conclusion, this study suggests serum uric acid levels may affect neither pathogenesis of MS nor activity of disease. Further studies are needed to clarify the role of uric acid in MS patients.
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Article Type: Original Article
EUR J GEN MED, Volume 6, Issue 3, July 2009, 166-169
https://doi.org/10.29333/ejgm/82663
Publication date: 15 Jul 2009
Article Views: 1565
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