The interaction of glutathione and thymoquinone and their antioxidant properties

Ferah Armutcu; Sumeyya Akyol; Omer Akyol

doi:10.29333/ejgm/89493

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Ferah Armutcu ¹ ^* , Sumeyya Akyol ², Omer Akyol ³

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¹ Professor of Medical Biochemistry, Private Esencan Hospital Esenyurt, Istanbul, Turkey² Associate Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA³ Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA^* Corresponding Author

Abstract

Protein S-glutathionylation has been regarded as one of the main mechanisms that control cell signaling and metabolic regulation. Several diseases including cardiovascular diseases, diabetes, neurodegenerative diseases and many types of cancer have been certainly found to be related with S-glutathionylation. It can be regarded as a promising area for therapeutic and diagnostic approaches in many diseases. In this mini review, we aimed to summarize and compare the interaction of glutathione (GSH) and thymoquinone (TQ), and elucidate the possible synergistic mechanisms of antioxidant and other beneficial effects.

Keywords

glutathione
glutathionylation
thymoquinone
Oxidative Stress

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

ELECTRON J GEN MED, Volume 15, Issue 4, August 2018, Article No: em59

https://doi.org/10.29333/ejgm/89493

Publication date: 15 Apr 2018

Article Views: 2963

Article Downloads: 3457

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Declaration of Conflict of Interest: No conflict of interest is declared by author(s).

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How to cite this article

Vancouver

Armutcu F, Akyol S, Akyol O. The interaction of glutathione and thymoquinone and their antioxidant properties. ELECTRON J GEN MED. 2018;15(4):em59. https://doi.org/10.29333/ejgm/89493

APA

Armutcu, F., Akyol, S., & Akyol, O. (2018). The interaction of glutathione and thymoquinone and their antioxidant properties. Electronic Journal of General Medicine, 15(4), em59. https://doi.org/10.29333/ejgm/89493

AMA

Armutcu F, Akyol S, Akyol O. The interaction of glutathione and thymoquinone and their antioxidant properties. ELECTRON J GEN MED. 2018;15(4), em59. https://doi.org/10.29333/ejgm/89493

Chicago

Armutcu, Ferah, Sumeyya Akyol, and Omer Akyol. "The interaction of glutathione and thymoquinone and their antioxidant properties". Electronic Journal of General Medicine 2018 15 no. 4 (2018): em59. https://doi.org/10.29333/ejgm/89493

Harvard

Armutcu, F., Akyol, S., and Akyol, O. (2018). The interaction of glutathione and thymoquinone and their antioxidant properties. Electronic Journal of General Medicine, 15(4), em59. https://doi.org/10.29333/ejgm/89493

MLA

Armutcu, Ferah et al. "The interaction of glutathione and thymoquinone and their antioxidant properties". Electronic Journal of General Medicine, vol. 15, no. 4, 2018, em59. https://doi.org/10.29333/ejgm/89493