The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia

Raida Ben Salah; Mona Snoussi; Nour Louati; Chebbi Donia; Faten Frikha; Mnif Hela; Bahloul Zouhir

doi:10.29333/ejgm/94112

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Raida Ben Salah ¹ ^* , Mona Snoussi ¹, Nour Louati ², Chebbi Donia ¹, Faten Frikha ¹, Mnif Hela ², Bahloul Zouhir ¹

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¹ Department of Internal Medicine, Hedi Chaker Hospital Sfax, Tunisia² Center of Transfusion, Hedi Chaker Hospital Sfax, Tunisia^* Corresponding Author

Abstract

Autoimmune Lymphoproliferative syndrome is an inherited disorder manifesting with autoimmune cytopenia, lymphadenopathy and splenomegaly. The differential diagnosis includes infections, autoimmune disorders or malignancies. The disease is characterized by accumulation of double negative (CD3+ CD4- CD8-) T cells (DNT) in the peripheral blood. Here we report the case of 19 years-old girl that was diagnosed as autoimmune Lymphoproliferative syndrome with a literature review.

Keywords

lymphoproliferative auto-immune syndrome
cytopenia

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

ELECTRON J GEN MED, Volume 15, Issue 5, October 2018, Article No: em78

https://doi.org/10.29333/ejgm/94112

Publication date: 23 Aug 2018

Article Views: 2066

Article Downloads: 1382

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Declaration of Conflict of Interest: No conflict of interest is declared by author(s).

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How to cite this article

Vancouver

Ben Salah R, Snoussi M, Louati N, Donia C, Frikha F, Hela M, et al. The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia. ELECTRON J GEN MED. 2018;15(5):em78. https://doi.org/10.29333/ejgm/94112

APA

Ben Salah, R., Snoussi, M., Louati, N., Donia, C., Frikha, F., Hela, M., & Zouhir, B. (2018). The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia. Electronic Journal of General Medicine, 15(5), em78. https://doi.org/10.29333/ejgm/94112

AMA

Ben Salah R, Snoussi M, Louati N, et al. The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia. ELECTRON J GEN MED. 2018;15(5), em78. https://doi.org/10.29333/ejgm/94112

Chicago

Ben Salah, Raida, Mona Snoussi, Nour Louati, Chebbi Donia, Faten Frikha, Mnif Hela, and Bahloul Zouhir. "The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia". Electronic Journal of General Medicine 2018 15 no. 5 (2018): em78. https://doi.org/10.29333/ejgm/94112

Harvard

Ben Salah, R., Snoussi, M., Louati, N., Donia, C., Frikha, F., Hela, M., and Zouhir, B. (2018). The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia. Electronic Journal of General Medicine, 15(5), em78. https://doi.org/10.29333/ejgm/94112

MLA

Ben Salah, Raida et al. "The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia". Electronic Journal of General Medicine, vol. 15, no. 5, 2018, em78. https://doi.org/10.29333/ejgm/94112