The Possible Immunological Pathways for the Variable Immunopathogenesis of COVID—19 Infections among Healthy Adults, Elderly and Children
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Ahmed S. Abdulamir 1 * , Rand R. Hafidh 2
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1 Professor in Virology and Infectious diseases, M.B., Ch.B., Ph.D. at Microbiology Department, College of Medicine, Alnahrain University, Baghdad, IRAQ2 Associate Professor in Biotechnology and Infectious diseases, Ph.D. at Microbiology Department, College of Medicine, University of Baghdad, Baghdad, IRAQ* Corresponding Author

Abstract

Novel Coronavirus, COVID-19 discovered in December, 2019 in Wuhan, China started a world-wide epidemic. It is not clear till now what is the pathogenesis of this virus infection in human or the exact strategies of host immune response in combating this novel threat to human beings. However, morbidity and mortality of COVID-19 infections vary widely from asymptomatic, mild to deadly critical. Strangely, children were found to be protected from severe or deadly critical infections, while elderly and immunocompromised adults are most affected badly by this virus. It is necessary to disclose the possible viral and host interactions that lead to such variable morbid effects among patients of COVID-19 infections.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

ELECTRON J GEN MED, Volume 17, Issue 4, August 2020, Article No: em202

https://doi.org/10.29333/ejgm/7850

Publication date: 21 Mar 2020

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