Clinical and therapeutic aspects in skin cancer: Clinical study in a tertiary center from Romania
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Mihaela Craescu 1 2 , Carmen Bobeica 3 , Elena Niculet 1 2 * , Carmina Musat 1 , Raul Mihailov 4 , Florin Ciprian Bujoreanu 2 3 5 , Laura Bujoreanu-Bezman 1 2 5 , Gabriel Murariu 6 , Andreea-Georgiana Dobre 7 , Alin Codrut Nicolescu 8 , Alin Laurentiu Tatu 2 9 10
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1 Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, ROMANIA2 Multidisciplinary Integrated Center of Dermatological Interface Research (MICDIR), “Dunărea de Jos” University, Galați, ROMANIA3 Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, ROMANIA4 Clinical Surgical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, ROMANIA5 Biomedical Doctoral School, “Dunărea de Jos” University, Galați, ROMANIA6 Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University, Galați, ROMANIA7 Department of Individual Sports and Kinetotherapy, Faculty of Physical Education and Sport, “Dunărea de Jos” University, Galați, ROMANIA8 Emergency Clinical Hospital Agrippa Ionescu, Bucharest, ROMANIA9 Clinical Medical Department, Faculty of Medicine and Pharmacy, “Dunărea de Jos” University, Galați, ROMANIA10 Department of Dermatology, “Sf. Cuvioasa Parascheva” Clinical Hospital of Infectious Diseases, Galați, ROMANIA* Corresponding Author

Abstract

Introduction: Skin cancer registers worldwide high morbidity and mortality rates, with costly medical services, its major histopathology subtypes being basal and squamous cell carcinoma, melanoma.
Materials and method: This 5-year retrospective study included 84 patients admitted to the “Sfântul Apostol Andrei” Emergency Clinical Hospital of Galați in the oncology and radiotherapy clinic during January 2018-October 2022.
Results: Skin malignancies represented 3.56% of the oncological cases admitted from January 2018 to October 2022. The most prevalent etiological factors were sun exposure and light-colored skin (84.52%). Most cases registered discomfort due to local and persistent itching (59.52%). Histopathologically, most cases were squamous cell carcinomas (51.19%). The most frequent treatment methods were surgical intervention (100%), radiotherapy (100%), chemotherapy (7.14%), immunotherapy (7.14%), with a 5-year survival rate of 95.23%.
Conclusions: The available screening programs help with skin cancer early diagnosis, leading to favorable outcomes and reducing complication risks.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 22, Issue 2, April 2025, Article No: em634

https://doi.org/10.29333/ejgm/15994

Publication date: 01 Mar 2025

Online publication date: 18 Feb 2025

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Article Downloads: 63

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