Exploring fracture risk assessment tool (FRAX®) for women 50 years and older: A cross-sectional study
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Lobna Gharaibeh 1 * , Mariam Alameri 2 , Zainab Lafi 3 , Rana K Abu-Farha 4 , Aseel Yaghi 1 , Navra Sahawneh 5 , Nadia Alkateeb 6 , Maryna Alfawair 6
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1 Biopharmaceutics and Clinical Pharmacy Department, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, JORDAN2 Department of Clinical Pharmacy and Pharmacy Practice, Yarmouk University, Irbid, JORDAN3 Pharmacological & Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, JORDAN4 Department, of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, JORDAN5 Alfuhies General Health Center, Ministry of Health, Amman, JORDAN6 Ain Albasha Comprehensive Health Center, Ministry of Health, Amman, JORDAN* Corresponding Author

Abstract

The fracture risk assessment tool (FRAX®) is useful in clinical practice for assessing ten-year major osteoporotic and hip fracture risk. This cross-sectional study aimed at assessing possible predictors of the FRAX® score for Jordanian women. Univariate and multivariate linear regression analysis was used to evaluate predictors of the FRAX® score. A total of 400 women were included in the study, hypertension was the most common medical condition, 66.3% (n = 265) of the participants did not have their vitamin D status checked, 9.0% of the respondents had insufficiency (n = 36), while 7.5% had deficiency (n = 30). Higher age at menopause and longer duration since menopause were predictors of higher scores for major osteoporotic fractures and hip fractures, with both p-values < 0.001. Using the FRAX® score for early identification of women with high risk, especially those with longer years of menopause provides an opportunity of early preventive measures.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, Volume 22, Issue 2, April 2025, Article No: em633

https://doi.org/10.29333/ejgm/15993

Publication date: 01 Mar 2025

Online publication date: 18 Feb 2025

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