The Effect of Sevoflurane and Desflurane on the Early Postoperative Cognitive Functions In Geriatric Patients
Halit Çobanoğlu 1, Aybars Tavlan 1, Ahmet Topal 1, Alper Kılıçaslan 1 * , Atilla Erol 1, Şeref Otelcioğlu 1
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1 Department of Anaesthesiology, Necmettin Erbakan University, Meram Medical Faculty Konya / Turkey* Corresponding Author

Abstract

Our aim was to compare the effects of desflurane and sevoflurane on cognitive functions of geriatric patients that were planned for elective surgery under general anestesia. After national ethical committee approval, 40 patients (aged 65-75 yr) were enrolled. Patients were allocated to either the desflurane (n=20) or the sevoflurane (n=20) group. In all patients anaesthesia will be induced with propofol and remifentanyl, and maintained with the anaesthetics desflurane, or sevoflurane, and remifentanyl. Emergence times from anaesthesia and Aldrete scores were recorded. Cognitive function will be evaluated with two cognitive test; Blessed Short Orientation Memory Concentration Test (BOMC) and standardized mini mental test (SMMT) preoperatively and postoperatively at 60, and 180 minute after extubation. The mean extubation time, eye opening time and Aldrete scores were similar in the desflurane and sevoflurane groups (p>0,05). There were no significant differences between the desflurane and the sevoflurane groups when the BOMC and MMST scores were compared preoperatively, and postoperatively at 60, and 180 min (p>0,05).The result of this study indicate that there is no difference between effects of desflurane and sevoflurane anesthesia on postoperatif cognitive functions in the elderly.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, Volume 10, Issue 1, January 2013, 32-38

https://doi.org/10.29333/ejgm/82365

Publication date: 09 Jan 2013

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